Top Conolidine alkaloid for chronic pain Secrets
Most recently, it's been discovered that conolidine and the above derivatives act around the atypical chemokine receptor three (ACKR3. Expressed in very similar locations as classical opioid receptors, it binds to a big range of endogenous opioids. Unlike most opioid receptors, this receptor functions for a scavenger and will not activate a 2nd mes